Originally, the building housed the First National Bank, The first half of the building was completed in 1912, and in 1924, an identical second part was added to complete it. Now it is PNC Bank.
Listing in 1893 newspaper for Mrs. J. T. McMahon selling dinnerware and teas. In 1897, saloon From 1930 to around 1965, was Gallagher Drug Company. In the 1960-70 it was an office for Skelton Lawyers. In 2005, the building became the Port City Cafe and Pub.
Listed in 1894 as Laubley & Son Saloon, in 1898 as Jacob Linck Saloon & Billiard Hall/ Roth Sporting Goods.
In 1921, it was the home of Queen City Restaurant. From 1937 onward, it has been used for various commercial stores.
Earliest listing for 416 Chillicothe is in 1892 as T. Schiff, salvage store. Next listing is in 1913-14, as the London Shop Men's Clothing. From 1914 to 1926, the Si Strauss & Company. Merit Shoes moved in in 1930, replacing the Princess Shoppe. In the 1940s, the Modern Shop, Collins Store until 1968, when Artwill opened.
Listings for 418 Chillicothe include: Henry Ruel market, 1908; Sugar Bowl , 1910; Senate Cafe; Bake Shop, 1920s, Artwil, 1930s-60s; The Book Rack, 1970s
In 1892, the Schloss Brothers & Company, stationers, was listed in the city directory. From 1918 to 1919, the building was Curtis & Shumway, and 1920s, it was Liberty Confectionary/Cafe. It has been used for various commercial businesses including a fuel company.
Scioto County Auditor records was built in 1900. From 1916 to 1985, it was S. S. Kresge Company 5 & 10 cent Store. From 1989 to 2001, it was Carrington's Outlet. In 2002, it became Diamond Gem Lending Company.
From 1926 ,was various retail stores including Star Credit Clothing Company and Berkeley Smith Inc. Women's Clothing. In 2009, it became Simon Kenton Council Boy Scouts of America.
The building at 320 Chillicothe Street was built by Phil Wolff in 1926 as a new location for Wolffs Men's Clothing .
This building was built in 1910 and remodeled in 1995. From 1926 to 1961, the building housed the W. T. Grant Company Inc. Department Store. In 1962 , the King's Dollar Store opened in the location. In the 1980s, it was Mike's Appliances. In 2011, it was purchased by Shawnee State University. Razed in 2023.
This building was built in 1907. From 1937 to 1962, it was Peoples Credit Clothing Store. From 1964 to 1971 it was Glad Tidings Book Store. From 1971 to the early 2000's, it was Bauer Graphics, a graphic design studio. In November 2015, the building was purchased by the Shawnee State University Development Foundation. Razed in 2023.
